Repeated vaccination is required to optimize seroprotection against H1N1 in the immunocompromised host
نویسندگان
چکیده
منابع مشابه
Prevalence of seroprotection against the pandemic (H1N1) virus after the 2009 pandemic.
BACKGROUND Before pandemic (H1N1) 2009, less than 10% of serum samples collected from all age groups in the Lower Mainland of British Columbia, Canada, showed seroprotection against the pandemic (H1N1) 2009 virus, except those from very elderly people. We reassessed this profile of seroprotection by age in the same region six months after the fall 2009 pandemic and vaccination campaign. METHO...
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Human immunodeficiency virus type 1 (HIV-1)-infected individuals, despite receipt of antiretroviral therapy (ART), often have impaired vaccine responses. We examined the role that immune activation and cellular phenotypes play in influenza A(H1N1) vaccine responsiveness in HIV-infected subjects receiving ART. Subjects received the H1N1 vaccine (15-µg dose; Novartis), and antibody titers at base...
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Immunocompromised patients are highly susceptible to infection with Pseudomonas aeruginosa. Our laboratory previously showed that intranasal administration of an attenuated Salmonella strain expressing the P. aeruginosa lipopolysaccharide O antigen was effective in clearing bacteria and preventing mortality in wild-type mice after intranasal challenge. We were interested in investigating the ef...
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The population of immunocompromised patients has multiplied greatly in recent years due to an expansion of indications for immunosuppressive therapies combined with improved survival following organ and bone marrow transplantation, cancer chemotherapy, and other chronic diseases requiring immunosuppressive therapy. Despite advances in prophylactic strategies and antimicrobial therapies, infecti...
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ژورنال
عنوان ژورنال: Haematologica
سال: 2010
ISSN: 0390-6078,1592-8721
DOI: 10.3324/haematol.2010.032664